Your Mom suffers from an incurable disease. It isn't deadly, but it causes her a good bit of pain, and can make her sick from time to time. On occasion (say 1-2 times a year) she needs some time in the hospital in order to re-adjust her meds and get nutrition and recover from bad bouts, etc.
Your career is at a standstill in your town and it would be better for you to move away. Also, your partner, whom you plan on marrying, hates where the two of you are and wants to continue his education in another state.
You have a sister that is staying in your town and is only a 10 minute drive from your mom, but she isn't always reliable.
Do you stay and risk a dead-end career and the loss of your future spouse, or do you move away and risk not being there if your mother needs you?