...to spend the rest of your life illiterate (the ability to read is removed from your brain). You cannot re-learn to read or else you lose the money
..to lose your long-term memory? For the rest of your life, your memory retention is only 2 years for all memories from this point on
...to gain an extra 30lbs and keep it? As long as you retain this weight, the money's yours
...to move to, and live in a third world country (say Guatamala). You can visit your family and friends as you like, but you would require a Visa to do so, as your new citizenship is now with your new country
...to never see your closest friend again?
...to never watch tv or see another movie ever again?