Nicest: A couple days ago I got a call from a bedridden neighbor. She had thrown up on the floor and needed someone to clean it because her daughter would be gone until late that night. I put on rubber gloves, got some bleach, and went over and cleaned up that terrible mess. She had been eating fish, so it smelled extra bad. Amazingly, I only gagged a few times.
Meanest: I once did the "Bloody Mary" thing with my little sister, who was about 8. I claimed to have seen something in the mirror, then quickly ran out of the bathroom and slammed the door shut behind me. I held it closed, and listen to her scream and beg me to open the door. I only let her out when my grandma slapped the back of my head.